Abstract

Introduction: Sino nasal inverted Papilloma (IP) is benign epithelial tumors, characterized by their capacity of bone destruction, tendency to relapse and malignancy potential. They represent 70% of the papilloma in the nasal cavity and 0.5% to 4% of neoplasms in the Para nasal sinuses. They appear at any age, with higher incidence in men (2:1); and most often affects a single nostril. Objective: Evaluate our experience in the diagnosis and treatment of Sino nasal inverted Papilloma, as well as the salinization and relapse incidence of HPV-related IP. Materials and methods: A retrospective study of Sino nasal Inverted Papilloma diagnosed in patients treated in the Otolaryngology service at the Hospital general de Agudos Dr. Ignacio Pirovano (CABA, Bs. as., Argentina), from 2015 to 2018. Results: 15 surgeries interventions were performed in patients with a sinonasal IP diagnosed from June 2015 to September 2018. The patients were in an age range between 35 and 75 years, whom 7 were women and 8 men. The average age was 53 years. 100% of the patients (n=15) were treated with endoscopic endonasal resection, and in 27% of these cases (n = 4) were combined with Caldwell-Luc approach. Conclusions: Sinus inverted Papilloma is a potentially aggressive benign tumor whose gold standard treatment is endoscopic approaches. In our experience the recurrence rate was 20%. In relation to the percentage of malignancy, which does not correlate with the bibliography since it arose in 40% of patients; only 27% of them were HPV-related.