Abstract

Purpose: Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrated source of platelet-rich proteins obtained from whole blood through centrifugation, which removes red blood cells. This study aims to evaluate the effectiveness of PRP in treating persistent corneal epithelial defects. Method: PRP eye drops were prepared and used by patient of corneal epithelial defect in post infectious corneal ulcer patients and effect was seen in terms of healing on slit lamp. Result: PRP contains high levels of PDGF, TGF, FGF, IGF 1&2, VEGF, EDGF, and Interleukins. PRP was used in 50 patients and the healing of corneal epithelial defect was evaluated. Conclusion: PRP is found to be efficacious in healing of corneal epithelial defect in post infectious corneal ulcer patients with minimal side effects.