Pharmaceutical Sciences & Analytical Research Journal ISSN: 2640-6659
Review Article
Synergistic Elegance: Harnessing Liposomes as Advanced Cosmetic Drug Delivery Systems with Phospholipids and Phenolic Components
Published: 2024-08-26

Abstract

Liposomes, widely embraced for their safety in cosmetic applications, have become integral to the beauty industry. Derived from biologically sourced phospholipids, these compounds exhibit a remarkable affinity for the skin’s surface. Not only are liposomes highly permeable, with significant storage capacity in the stratum corneum, but they also act as dynamic agents on the skin. On-going research in liposomes primarily focuses on their potential in cosmetic drug delivery. Formulations of liposomes, sourced from diverse phospholipid origins such as egg and soya, undergo differentiation based on their impact on skin parameters, including water content, elasticity, and barrier function. The diverse array of phospholipids within liposomes contributes to a spectrum of effects on human skin. Phenolic compounds derived from plant metabolites present antioxidant and anti-inflammatory activities. However, the stability and bioactivity of these compounds are contingent upon careful extraction processes, given their sensitivity to light and heat sources. Challenges such as rapid metabolization, low solubility, and limited bioavailability characterize phenolic compounds. This article not only imparts valuable insights into the role of liposomes, particularly those containing phospholipids and phenolic compounds, in cosmetics but also sheds light on innovative methods in liposome formulation. Additionally, it delves into a discussion about liposomes already present in the cosmetic market, offering a comprehensive overview of their potential and current applications in the beauty industry.

Keywords

Liposomes; Phospholipids; Phenolic Compounds; Cosmetics