Abstract

Abstract

Introduction

Due to the increase in the demand of renal grafts, the criteria for organ acceptance have been widened. It has been accepted the definition of expanded criteria donor (ECD) and it has been developed new extraction techniques such as organ donation after circulatory death (DCD). In order to better preserve the renal grafts and optimize their function, graft perfusion techniques have been developed through different systems, which allow an increase in the hours of cold ischemia.

Material and Methods

Data base is created with the inclusion criteria where both donor kidneys were transplanted in different receptors, preserving one kidney in cold storage (CS) and the other using a continuous pulse machine perfusion device. Lifeport Kidney Transporter device is used in this study. T student for independent means analysis is carried out with the objective to find statistically significant differences in the analytical and functional parameters.

Results

There were no differences on receptors characteristics. It was found statistically significant difference in time of cold ischemia between cold storage and machine perfusion (p= 0.00). It is remarkable that diuresis, creatinine and urea seem to be better on MP group even when p value is not significant. Postsurgical complications, blood transfusions and hospitalization days are also less on MP group.

Conclusion

The preservation of the renal graft by MP achieves similar short-term results compared to cold storage irrespective of the greater time of cold ischemia.