Objective: To assess corneal endothelial cell density in individuals having different refractive errors including Myopia, Hyperopia,

and Astigmatism.

Method: A descriptive cross-sectional study was done to assess the endothelial cell count of the cornea in different refractive

errors using a Performa. Data from 71 individuals (24 myopes, 24 hyperopes, and 23 astigmatic) with different refractive errors

were taken using a non-contact specular microscope (Topcon SP2000P, Tokyo, Japan). Visual acuity was recorded on the Snellen

chart and then both subjective and objective refractions were done to find the best corrected visual acuity (BCVA). An objective

refraction was done using an auto refractometer and then was verified by subjective refraction. Patients with contact lens usage

history, previous ocular surgery history, and ocular pathologies were excluded. Data was entered and analyzed with SPSS-25.

Results: The mean of endothelial cell density (ECD) between the three groups was compared. There was a difference in means

values of ECD among three groups i.e., myopes, hyperopes, and astigmatic but no significant differences in ECD between myopic,

hyperopic, and astigmatic eyes were found (p=0.121(RE) and p=0.106 (LE); 1-way ANOVA test).

Conclusion: It is concluded from the study that Endothelial cell density (ECD) is not associated with the three main type of

refractive errors that is myopia, hyperopia and astigmatism, as we found difference in mean ECDs in these groups but this

difference was not significant.