Abstract

Diabetic retinopathy (DR), a common microvascular complication of diabetes mellitus, represents a significant cause of vision impairment and blindness worldwide. As a cornerstone of DR management, Panretinal Photocoagulation (PRP) aims to mitigate proliferative diabetic retinopathy (PDR) but carries potential risks, including changes in macular thickness, which may exacerbate vision loss. This study assesses the impact of a single session of PRP on macular thickness in patients with PDR. Methods: Conducted at Lahore General Hospital’s Department of Ophthalmology, this quasi-experimental study evaluated macular thickness pre- and post-PRP in 100 eyes of diabetic patients aged 18-65, using the OCT-Topcon 3D for measurements. Participants underwent a standardized PRP procedure with an Argon Laser, and macular thickness data were analyzed using SPSS, focusing on changes documented at one week post-treatment. Results: The study demonstrated a statistically significant increase in macular thickness post-PRP (p