Abstract

Barbiturate poisoning, a critical medical condition arising from the toxic effects of excessive barbiturate exposure, presents a complex clinical challenge. This review explores the multifaceted landscape of barbiturate poisoning, encompassing its historical context, causes, clinical manifestations, diagnostic approaches, and therapeutic interventions. Barbiturates, once prominent for their sedative properties, have witnessed a decline in medical use due to safety concerns and the advent of alternative medications. Causes of poisoning range from intentional overdoses in suicide attempts to accidental ingestion, misuse of prescription medications, and recreational or illicit use. Barbiturate overdose can cause central nervous system depression, respiratory failure, and circulatory collapse. It is important to recognize and treat barbiturate poisoning as soon as possible. Laboratory testing and clinical evaluation are used to provide a diagnosis, and emergency response plans put a priority on receiving medical care as soon as possible. Treatment modalities include supportive care, activated charcoal administration, and specific antidotes in severe cases. Preventive measures emphasize secure medication storage, education on the risks of misuse, and mental health support. This abstract provides a comprehensive overview of barbiturate poisoning, emphasizing the need for heightened awareness, early intervention, and a holistic approach to mitigate its impact on public health.