Abstract

Primary central nervous system lymphoma (PCNSL) is a non-B-cell Hodgkin’s lymphoma (NHL) that primarily affects the brain, spinal cord, leptomeninges, or eye without systemic involvement. Diffuse large B cell (DLBC) lymphomas account for around 95% of primary CNS lymphomas; the remaining accounts for low-grade B cell lymphomas, T cell lymphomas, and Burkitt lymphomas. Matrix regimen is the current standard of care for PCNSL. We have used this regimen for our patients of PCNSL to understand its applicability in LMICs. This Manuscript details our early experience.