We report here a case of 25 year old lady diagnosed with acute lymphoblastic leukemia (ALL) who was on chemotherapy since 5 months, complained to headache. Headache was evaluated. MRI of the brain showed ring enhancing lesion in the left parieto-occipital region. CSF analysis was done- routine biochemical tests, cultures and PCR based tests were done. PCR test was positive for aspergillus species. As the patient was diagnosed with central nervous system (CNS) aspergillosis, she was started on voriconazole. Patient improved clinically
Acute Lymphoblastic Leukemia (ALL); Central Nervous System (CNS); Aspergillosis