Abstract

Sexual dysfunction is a disturbance in sexual function that may be experienced by both males and females. It may be caused by mental health disorders, namely depression, anxiety, schizophrenia, and bipolar disorder. It may also be caused by the pharmacologic treatments used to treat the common mental health conditions. Antipsychotics increase the risk of sexual dysfunction in relation to their affinity to dopamine as well as acetylcholine, histamine, and the alpha receptors. The antidepressants that have an affinity for serotonin, have a greater risk of sexual dysfunction. Of the mood stabilizers, lithium is considered to have the highest incidence of sexual dysfunction this may be attributed to its relaxation of the corpus cavernosa and is seen even more so when combined with a benzodiazepine. When sexual dysfunction is a concern the psychotropic choice should be evaluated for its potential to contribute. Other appropriate options are to adjust the dose of the agent or use adjunct medication to help address the dysfunction while still utilizing the psychotropic of choice.