Abstract

Phytosome is a complex obtained by reaction between a natural product and phospholipids in a suitable solvent; the phospholipids-product interaction occurs as a result of hydrogen bond formation between the phospholipids phosphate and ammonium groups of the polar head and those of the natural product substrate that can be revealed using spectroscopic methods. Size of phytosome varies from 50 nm to a few hundred μm. It can be deduced that the fatty chain gives unchanged signals both in free phospholipids and in the complex and that can be detected by FTIR data, which indicates that long aliphatic chains are wrapped around the active principle producing lipophilic envelope [1].