Abstract

Most assuredly diabetic foot ulcer can influence to infection, gangrene, amputation, and even death if necessary care is not needed. On the other hand, once diabetic foot ulcer has advanced, there is an escalated peril of ulcer progression that perhaps finally influence to amputation. Overall, the rate of lower limb amputation in patients with diabetes mellitus is fifteen fold higher than patients without diabetes mellitus. Debridement appears to de-escalate bacterial counts and enliven generation of local growth factors. This method also decreases pressure, evaluates the wound bed, and facilitates wound drainage. Debridement is the takeoff of necrotic and senescent tissues as well as foreign and exposed materials from a wound, which is considered as the primary and the consummate significant therapeutic step influencing to wound closure and de-escalate in the possibility of limb amputation in patients with diabetic foot ulcer. Enzymatic debridement is a method of debriding devitalized tissue by topical enzymes such as collagenase, fibrinolysin, or papain. The intention of this review article is to encapsulate application of debridement in diabetic foot ulcer advanced from diabetes mellitus as complications and also articulate its advantages for diabetic foot ulcer complication management.