Barrett's esophagus is a disease that commonly manifests itself more common in white males, and its prevalence increases with aging, although there are no precise statistics it is believed that around one million Argentines suffer from this precancerous pathology. For this, it is recommended to perform single esophagoscopy in individuals with persistent symptoms of gastroesophageal reflux at 50 years of age. Due to the chronic irritation produced by the abnormal reflux of gastric acid into the esophagus, after several years of irritation, the tissues of the esophageal junction with the stomach develop a defense covering with stomach tissue to be able to resist the burning of the acid. In these new tissues, goblet cells similar to those of the small intestine develop, but with the difference that these new cells are not the same and have the potential to become a gastric cancer of the esophageal junction with the stomach.