Abstract

Selenomethionine (2-amino-4-methylselanylbutanoic acid) is a Se-containing naturally occurring chiral amino acid and is well known for its dietary and biological importance and has been used as a source of Se in humans, other mammals and plants. L-SeMet is better absorbed and better incorporated into the body than any other known form of selenium. This is due to the presence of active functional groups carboxyl (-COOH) and amino groups (-NH2) in their unique and simple

structure. In this review attempts are being done the enantiomeric separation of Selenomethionine by using chromatographic techniques and deals with the application of: thin layer chromatography by direct method using chiral selector as, chiral inducing reagents and chiral impregnating reagent. High-performance liquid chromatography, by direct method using chiral stationary phase columns and, by indirect method using chiral derivatizing reagents.