Abstract

Kaposi’s disease is a multifocal disease affecting the skin and viscera. Four clinical variants have been distinguished: classic KS, endemic KS, HIV-related KS and iatrogenic KS (iKS), the latter occurring in patients undergoing immunosuppressive treatments for organ transplant, malignant processes or immune-mediated diseases. We report a case of KS associated with glucocorticoids therapy for chronic arthralgia. Clinical manifestations generally resolve after immunosuppressive drugs are reduced or discontinued, whereas maintaining immunosuppression frequently leads to further disease progression. Prognosis also depends on the severity at presentation. All dermatologists dealing with immune suppressors must be aware and have a high index of suspicion when a patient present with rapidly progressive violaceous papules.