Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has claimed the lives of over seven million people. Millions more are living with its consequences. COVID-19 has wreaked havoc across the globe without respect for international borders and sparing none. It has affected rich-poor, young-old, men-women - literally everyone. The etiologic agent of COVID-19 is the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that has the ability to infect all organs of the body, although the respiratory system is the primary site of infection. The nervous system is also vulnerable. Infection of the brain leads to neurological complications, including cognitive dysfunction and psychiatric problems. Difficulty remembering, thinking and confusion, often collectively termed as ‘brain fog’, are very common neurological symptoms of SARS-CoV-2 infection of the brain. The present review has aimed to describe the various neurological complications associated with COVID-19, highlighting the mechanisms of neuroinvasion and neurological damage, common neurological symptoms, and the major neurological disorders.