Abstract

Several infectious pathogens have emerged in the past posing a great challenge to the public health authorities throughout the world. Fungal infections are considered as a neglected threat to global human health. Emergomycosis, an emerging fungal infection caused by the genus Emergomyces within the family Ajellomycetaceae, presents significant problems in diagnosis and management, particularly among immunocompromised individuals. This thermally dimorphic pathogen, previously classified under Emmonsia, exhibits diverse clinical manifestations, including cutaneous lesions, pulmonary disease, and systemic dissemination. Diagnostic hurdles involve histopathology, fungal culture, and molecular techniques, thus underscoring the need for standardized diagnostic criteria. Treatment primarily relies on antifungal agents, emphasizing the importance of following established guidelines for endemic mycoses. Enhanced clinical awareness, collaborative efforts among healthcare providers and microbiologists, and robust public health strategies are essential for improving surveillance, diagnostics, and patient outcomes in emergomycosis.