Abstract

SCD affects about 6.4 million people globally, with over 5 million in sub-Saharan Africa. Sickle cell disease in pregnancy poses significant challenges to both the fetus and the mother, Pregnancy in patients with sickle cell disease (SCD) has also been a challenge for both hematologists and obstetricians. Despite the improvement in care for the patient with SCD, it has been a challenge to manage pregnant women with sickle cell disease in a lower resource setting. This article focuses on the discussion of management options that can be contextualized in lower-resource countries including Uganda to reduce the challenges that health care professionals face in managing SCD in pregnancy. It highlights the key aspects of preconception, antenatal, intrapartum, and postpartum care of SCD in pregnancy. Our emphasis on the prevention and management of the complications based on the current literature, which are cost-effective.