Abstract

Henoch-Schonlein Purpura (HSP) also known as IgA vasculitis, is an immune complex-mediated small vessel vasculitis that primarily affects children below 10 years old. Adult onset HSP or IgA vasculitis, is indeed rare compared to childhood onset. While HSP predominantly affects children especially aged 4 to 6, adult cases account only for about 10-20% of all HSP cases. What makes adult-onset HSP particularly noteworthy is not just its rarity but also its more severe clinical course. Renal involvement is significantly more frequent and severe in adults. With up to 50% or more shows signs of nephritis, and some progressing to renal insufficiency. Adults often require more aggressive treatment and have longer hospital stays (average of 10.2 days vs 4.3 days in children). The prognosis is generally less favorable in adults, with slightly lower complete recovery rate (90% in adults vs nearly 99% in children). So, a 26-year-old female presenting with HSP is not only uncommon but also clinically significant due to the higher risk of complications especially renal. The treatment includes intravenous antibiotics and injection dexamethasone and oral prednisolone.