Clinical Neuroscience & Neurological Research International Journal ISSN: 2689-6001
Review Article
Role of Endovascular Neurosurgery in Acute Ischemic Stroke: Optimal Timing for Mechanical Thrombectomy in Extended Time Windows
Published: 2025-02-05

Abstract

This review discusses mechanical thrombectomy (MT) as a key treatment for acute ischemic stroke (AIS) caused by large vessel occlusions (LVOs). MT aims to rapidly restore blood flow using devices like stent retrievers and aspiration catheters. The treatment window has expanded to 24 hours based on advanced imaging. Successful MT involves reperfusion, not just recanalization, with a target of mTICI grade 2b/3. Time is critical for successful outcomes. The article also outlines patient selection, treatment strategies, and challenges, particularly in developing countries. Direct to angiosuite strategies and ongoing research are focused on improving workflows and expanding treatment options.

Keywords

Endovascular Therapy; Mechanical Thrombectomy; Acute Ischemic Stroke; Stent Retriever